Domaine Pierre Usseglio is a 53-acre estate in Chateauneuf-du-Pape, in the Rhone Valley. Founded in the early 20th century by an Italian family from Piedmont, the estate remains in the hands of the Usseglio family. Specifically it is now run by brothers Jean-Pierre and Thierry Usseglio, who added 20 acres of old vine vineyards and have fine-tuned winemaking at the estate. The estate grows Grenache, Syrah, Mourvedre and Cinsault and produces a total of about 70,000 bottles annually. However, there is a much more limited production of the two signature cuvees, which are Chateauneuf-du-Pape Cuvee du Mon Aieul, and Chateauneuf-du-Pape Reserve des Deux Freres. The Reserve des Deux Freres is selected by the brothers as the best of the best. Both luxury cuvees win consistent praise from wine reviewers.